They differ in that they can be easily changed and provide a bit more space to describe whatever it is you feel relevant.
Quotes from famous people that you admire, agree with or want to emulate are quite popular in tag lines, as are truisms and lines from famous movies or songs.
Some of the newer, younger-focused or speed dating sites ask only for a tag line and nothing else - even more the reason to ensure yours is well crafted.
Tag lines are very similar to handles, in that they offer a very short space with which to impress or attract someone.
If so, try writing a sentence or two that describes why that place is special to you.
For instance, you may spend a lot of time in coffee shops writing on your laptop, reading a book or chatting with friends.
The problem with using any of these kinds of pieces as your tag line is that others are probably thinking the same thing.